Resources

New publication on the use of unmanned aerial vehicles for surveillance and control of vectors of malaria and other vector-borne diseases is  available in the Malaria Journal this month.

Access available via download or at Malaria Journal  https://malariajournal.biomedcentral.com/articles/10.1186/s12936-022-04414-0#:~:text=Consequently%2C%20it%20is%20essential%20for%20malaria%20researchers%20and,possible%20additions%20to%20the%20toolkit%20%5B%204%20%5D.

New publication on a new WHO bottle bioassay method to assess the susceptibility of mosquito vectors to public health insecticides is  available in the journal Parasites & Vectors this month.

Access available via download or  at Parasites & Vectors https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-022-05554-7

SOP – Removal of ant infestations from experimental huts. Updated: 04.01.2023.

Updated: 01.2023

Scoring mosquitoes after hut IRS. Updated 01/2023

SOP –  Preparation of sugar-soaked cotton wool for feeding adult mosquitoes in holding cages or during transportation between the laboratory and field. Updated: 04.01.2022.

SOP –  Mosquito collections from experimental huts. Updated 04.01.2023

SOP – Preparation of experimental huts for evaluation of IRS. Updated July 2022.

SOP – Spraying with the potter tower. Updated July 2022.

SOP – IRS Block Preparation. Updated July 2022.

SOP – Indoor residual spraying of experimental huts for evaluation of insecticides. Updated July 2022.

SOP – Cone bioassay on IRS treated surfaces in experimental huts. Updated July 2022.

SOP – Cone bioassay of treated blocks. Updated July 2022

SOP – Methods for monitoring the durability of dual-AI insecticide-treated nets containing a pyrethroid plus pyriproxyfen (PPF)

SOP – Methods for monitoring the durability of dual-AI insecticide-treated nets containing a pyrethroid plus piperonyl butoxide (PBO)

SOP – SOP: Methods for monitoring the durability of dual-AI insecticide-treated nets containing a pyrethroid plus chlorfenapyr (CFP)

SOP: Strain characterisation of resistant mosquitoes for monitoring bioefficacy in ITNs treated with two active ingredients (Dual-AI ITNs)

SOP – Experimental hut preparation and running. Updated May 2022

SOP – Net washing for semifield trials. Updated May 2022

SOP – Net washing for laboratory LLIN trials. Updated May 2022

SOP: Cutting and preserving net samples for chemical analysis. Updated May 2022.

Tunnel test SOP. Updated May 2022.

Cone bioassay SOP. Updated May 2022.

Raising the Floor on Nets May 2022 Convening: Day 3 Consolidated Presentations

Raising the Floor on Nets May 2022 Convening: Day 1 Consolidated Presentations

Raising the Floor on Nets Convening on ITN Quality and Performance

May 17 – 19, 2022. Liverpool, United Kingdom

The convening was a three-day, in-person workshop hosted by I2I and CHAI in Liverpool, UK.

It was the second such meeting, following the first convening (December 2021). The primary aim of the meeting was to outline a framework approach to ITN quality and performance, discuss major challenges around net quality and performance and opportunities to resolve these challenges, and to chart a way forward.

The objectives of the second meeting were:

1. Provide an update on the activities prioritized following the first convening in December 2021.
2. To present an overview of factors that influence and drive net quality and performance, with a focus on post-shipment issues.
3. To discuss potential solutions and pathways to fundamentally improve ITN quality and performance while addressing program country concerns.
4. To build consensus and buy-in for these solutions among key stakeholders.

New publication on protocol development to characterise resistant mosquitoes to support testing of dual-AI ITNs available in the journal insects this month.

Access available via download or MDPI at https://www.mdpi.com/2075-4450/13/5/434

A new method for measuring the effect of pyriproxyfen on mosquito fertility using a machine learning approach has been published.

Using a Convolutional Neural Network (CNN) model, researchers were able to automatically classify the fertility status of ovaries from PPF-exposed female mosquitoes. This recent work by members of I2I was published as part of the special issue on mosquito control in the journal Insects.

Experts have published updated protocols for assessing the durability of insecticide-treated bednets containing second active ingredients to fight insecticide resistance.

Following a recent consultation of relevant stakeholders, of university researchers, research organisations involved in ITNs durability monitoring studies, and procurement bodies, a new proposed set of guidelines and SOPs for assessing the durability of several  dual-AI ITNs was agreed. The work is now published in the special issue on insecticides for mosquito control in the journal Insects. The publication focuses on the methods used to develop this set of optimized SOPs, which assess the bioefficacy of nets containing a pyrethroid plus either chlorfenapyr, PBO or PPF. The methods and SOPs have been discussed and agreed with all the relevant stakeholders. 

I2I has partnered with the Bill and Melinda Gates Foundation (BMGF) and the Clinton Health Access Initiative (CHAI) to co-host a convening addressing issues pertaining to ITN quality and performance.

The convening, from the 14-16^th December, brings together stakeholders from across the ITN product development and delivery spectrum. Consisting of manufacturers, procurers, country programs, implementation partners and WHO the convening aims to discuss perceptions, challenges and successes in ITN development and quality management.

I2I and CHAI opened the meeting on December 14th by presenting an overview of the key issues.

ARCHIVED – SOP Net washing for Phase II LLIN Trials

Archived SOP: Tunnel Test

ARCHIVED – SOP Net washing

ARCHIVED – SOP for Cutting and preserving net samples for chemical analysis

Archived: SOP Cone Bioassay

Archived: 01.2023

ARCHIVED – SOP on Preparation of  sugar-soaked cotton wool for feeding adult mosquitoes in holding cages or during transportation between the laboratory and field

Archived: 01.2023

ARCHIVED – Removal of ant infestations from experimental huts.

Archived – SOP for Mosquito collections

This report includes:

• Summary of the registration authorities and process for each country, including relevant collaborative efforts
• Overview of the key authorities and legislation
• Detailed registration process
• Dossier overview
• Detail on enabling environment

Este relatório inclui:

• Visão de alto nível das autoridades de registro para 48 países e requisitos de registro para 20 países
• Resumo dos desafios de registro para produtos de VC em todo o continente com base em mais de 130 entrevistas e visitas no país
• Tabela de resumo das autoridades de registro de VC, processo e requisitos para 12 países em foco

Ce rapport comprend:

• Vue d’ensemble des autorités d’enregistrement de 48 pays et des exigences d’enregistrement pour 20 pays
• Résumé des défis d’enregistrement des produits de CV à travers le continent sur la base de plus de 130 entretiens et visites dans les pays
• Tableau récapitulatif des autorités d’enregistrement, du processus et des exigences d’enregistrement des CV pour 12 pays cibles

This report includes:

• High-level view of registration authorities for 48 countries and registration requirements for 20 countries
• Summary of registration challenges for VC products across the continent based on over 130 interviews and in-country visits
• Summary table of the VC registration authorities, process, and requirements for 12 focus countries