Resources

New publication on protocol development to characterise resistant mosquitoes to support testing of dual-AI ITNs available in the journal insects this month.

Access available via download or MDPI at https://www.mdpi.com/2075-4450/13/5/434

A new method for measuring the effect of pyriproxyfen on mosquito fertility using a machine learning approach has been published.

Using a Convolutional Neural Network (CNN) model, researchers were able to automatically classify the fertility status of ovaries from PPF-exposed female mosquitoes. This recent work by members of I2I was published as part of the special issue on mosquito control in the journal Insects.

Experts have published updated protocols for assessing the durability of insecticide-treated bednets containing second active ingredients to fight insecticide resistance.

Following a recent consultation of relevant stakeholders, of university researchers, research organisations involved in ITNs durability monitoring studies, and procurement bodies, a new proposed set of guidelines and SOPs for assessing the durability of several  dual-AI ITNs was agreed. The work is now published in the special issue on insecticides for mosquito control in the journal Insects. The publication focuses on the methods used to develop this set of optimized SOPs, which assess the bioefficacy of nets containing a pyrethroid plus either chlorfenapyr, PBO or PPF. The methods and SOPs have been discussed and agreed with all the relevant stakeholders. 

I2I has partnered with the Bill and Melinda Gates Foundation (BMGF) and the Clinton Health Access Initiative (CHAI) to co-host a convening addressing issues pertaining to ITN quality and performance.

The convening, from the 14-16^th December, brings together stakeholders from across the ITN product development and delivery spectrum. Consisting of manufacturers, procurers, country programs, implementation partners and WHO the convening aims to discuss perceptions, challenges and successes in ITN development and quality management.

I2I and CHAI opened the meeting on December 14th by presenting an overview of the key issues.

This report includes:

• Summary of the registration authorities and process for each country, including relevant collaborative efforts
• Overview of the key authorities and legislation
• Detailed registration process
• Dossier overview
• Detail on enabling environment

Este relatório inclui:

• Visão de alto nível das autoridades de registro para 48 países e requisitos de registro para 20 países
• Resumo dos desafios de registro para produtos de VC em todo o continente com base em mais de 130 entrevistas e visitas no país
• Tabela de resumo das autoridades de registro de VC, processo e requisitos para 12 países em foco

Ce rapport comprend:

• Vue d’ensemble des autorités d’enregistrement de 48 pays et des exigences d’enregistrement pour 20 pays
• Résumé des défis d’enregistrement des produits de CV à travers le continent sur la base de plus de 130 entretiens et visites dans les pays
• Tableau récapitulatif des autorités d’enregistrement, du processus et des exigences d’enregistrement des CV pour 12 pays cibles

This report includes:

• High-level view of registration authorities for 48 countries and registration requirements for 20 countries
• Summary of registration challenges for VC products across the continent based on over 130 interviews and in-country visits
• Summary table of the VC registration authorities, process, and requirements for 12 focus countries