About Us
Our mission is to reduce the impact of vector-borne diseases and contribute to their eventual elimination by improving the product development landscape for vector control tools, supporting enhanced evaluation processes, facilitating sustained quality of vector control products and improving their judicious and safe use with a focus on shortening time to market.
Our vision is a development environment for vector control products conducive to dialogue, innovation and investment and which efficiently delivers a steady stream of new, quality tools to those who need them most, and safeguards their continued effectiveness.
Rationale
Approximately 80% of the global population is at risk from vector-borne disease leading to over 700,000 deaths annually, predominantly in sub-Saharan Africa. Vector borne diseases, such as malaria, dengue, yellow fever and Zika and chikungunya pose a huge threat to the world, affecting not only health outcomes, but also serve to slow economic growth and…
READ MOREApproach
I2I’s work focuses on four overarching objectives:
- Innovation: Creating a more conducive environment for innovation and product development;
- Efficiency: Improving evaluation pathways to allow streamlined data generation to accelerate registration and uptake of new tools;
- Quality: Developing rigorous quality assurance systems to ensure the lasting impact of new products;
- Dialogue: Improving dissemination and understanding of WHO pre-qualification processes with vector control stakeholders;
I2i convenes vector control stakeholders such as global and country policy makers, product developers, donors, regulators, academia and programme implementers to streamline the evaluation and registration of new vector control tools.
Areas of Involvement
Leadership Team
Angus Spiers
Director
[email protected]
Angus leads the strategic agenda of i2i and manages the relationships with all major stakeholders. His role is focussed on finding stakeholder consensus on shared challenges and catalysing solutions to these. Prior to this role, he was Senior Malaria Advisor at the President’s Malaria Initiative. He formerly served as UNICEF’s Regional Malaria Advisor in Angola, as PSI’s Deputy Director of Malaria and Child Survival, and as a Senior Technical Advisor at USAID/PMI. Angus holds a PhD from the Liverpool School of Tropical Medicine.
Alison Reynolds
Technical Programme Manager
[email protected]
Alison oversees the programme and financial management of i2i activities and facilitates communications and collaboration across in-country partners, regulators, field implementers, malaria control programmes and other stakeholders. She also has particular involvement in coordinating the activities of the GLP and Country Registration workstreams and disseminating outputs. Alison has over 15 years’ experience in project management in academic and operational research including positions with the Malaria in Pregnancy Consortium at LSTM and the Malaria Modelling Research Group at Imperial College London. More recently Alison has managed projects in the LSTM Vector Biology Department focusing on the implementation of digital tools to facilitate better data driven decision making and capacity strengthening for vector borne-disease control programmes.
Angus Spiers Director
Angus leads the strategic agenda of i2i and manages the relationships with all major stakeholders. His role is focussed on finding stakeholder consensus on shared challenges and catalysing solutions to these. Prior to this role, he was Senior Malaria Advisor at the President’s Malaria Initiative. He formerly served as UNICEF’s Regional Malaria Advisor in Angola, as PSI’s Deputy Director of Malaria and Child Survival, and as a Senior Technical Advisor at USAID/PMI. Angus holds a PhD from the Liverpool School of Tropical Medicine.
Alison Reynolds Technical Programme Manager
Alison oversees the programme and financial management of i2i activities and facilitates communications and collaboration across in-country partners, regulators, field implementers, malaria control programmes and other stakeholders. She also has particular involvement in coordinating the activities of the GLP and Country Registration workstreams and disseminating outputs. Alison has over 15 years’ experience in project management in academic and operational research including positions with the Malaria in Pregnancy Consortium at LSTM and the Malaria Modelling Research Group at Imperial College London. More recently Alison has managed projects in the LSTM Vector Biology Department focusing on the implementation of digital tools to facilitate better data driven decision making and capacity strengthening for vector borne-disease control programmes.
Steering Committee
- Provide independent expertise and actionable guidance to support strategic direction of I2I programme;
- Agree objectives and workplans with I2I Leadership Team;
- Promote accountability of the I2I Leadership Team in attaining programme objectives;
- Work to actively support I2I to achieve its aims and objectives;
- Monitor progress and performance of the I2I programme;
Mark Hoppe
IRAC and Methods Representative
Syngenta
Senior Team Leader, Public Health
Mark Hoppé is a Public Health entomologist with 30 years’ experience of research, development and advocacy in agricultural and public health insect control. He is currently involved in the development of novel solutions for the control of insects of public health importance, working for Syngenta in Switzerland. Mark studied Crop Protection at Bath University, and holds an MBA in technology management. He is also the chair of the Insecticide Resistance Action Committee’s (IRAC) Public Health team, co-chairs the Roll Back Malaria VCWG’s Integrated Vector Management (IVM) and Insecticide Resistance Management (IRM) workstream, and is a Fellow of the Royal Entomological Society.Chris Kanema
Regulatory Representative
Zambia Environmental Management Agency
Principal Investigator & Head Pesticides & Toxic Substances
Christopher Kanema works for the Zambia Environmental Management Agency (ZEMA) as Principal Inspector and Heads the Unit responsible for sound management of Pesticides and Toxic Substances in Zambia. He has coordinated several projects in Zambia on sound management of chemicals in general and pesticides in particular. He is currently the focal point for the Rotterdam Convention on Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade as well as the focal point of the Minamata Convention on Mercury. In his capacity as a focal point, he has represented Zambia in the Conference of the Parties meetings. He is a member of several Technical Committees including the Southern African Pesticides Regulators Forum (SAPReF) and I2I.Corine Karema
Africa Policy Representative
African Leaders Malaria Alliance
Malaria Senior Programme Officer
Corine Karema is the former Director of the Rwanda National Malaria Control Program (NMCP), where she served in this role for ten years (2006 – 2016). Also, from 2011 to May 2016, she was the head of Malaria & Other Parasitic Diseases (Neglected tropical diseases) Division – Rwanda. During her time at the NMCP, she led the development of malaria control strategies, policies, and research, which has guided the implementation of evidence-based malaria control interventions resulting in increased coverage of critical malaria control interventions with important reductions in malaria morbidity and mortality in Rwanda. Her research has mainly focused on malaria, NTDs, Maternal and child health, as well as epidemiological and public health research. Corine was also the Co-chair of the East African Roll Back Malaria (RBM) Network Coordination committee and member of the diverse WHO scientific and advisory committees including the Global Malaria Control and Elimination technical working group; WHO Steering committee of the Global Technical Strategy for Malaria control and elimination 2016-2030 and RBM GMAP II Task Force.Marion Law
Regulatory Representative
WHO PQ
Group Lead, WHO Pre-Qualification
Marion Law, the Team Lead of the Vector Control Products Team, is a microbiologist with research experience in the area of antibiotic and microbial resistance. Before joining WHO three years ago, she held a number of senior executive positions in Health Canada which included, leading health product evaluation, science policy development and regulatory science operations in the areas of pharmaceuticals, medical devices, control drugs and substances, blood products, and biotechnology drugs as well as pesticides and pest control products. As a previous Chief Registrar of the Pest Management Regulatory Agency of Health Canada, and more recently the Director General of the Therapeutic Products Directorate, Health Canada she has extensive international experience including as head of the Canadian delegation to NAFTA and also to the OECD where she was the Chair of the OECD Working Group on Pesticides.Dave Malone
Product Development and GLP Representative
Bill & Melinda Gates Foundation
Senior Programme Officer, Vector Control, Malaria
David Malone, Senior Programme Officer for Vector Control at the BMGF, is an entomologist, with research experience in the area of insecticide resistance and vector biology. Before joining BMGF, David held a role as Senior Business Development Manager for Sumitomo Chemical and prior to this was Technical Manager at the Innovative Vector Control Consortium (IVCC) in Liverpool. Previously he worked as a civilian medical entomologist for the British Military, at the Cayman Islands Mosquito Research and Control Unit and as Director of Research and Technical Services for the Florida based company Adapco.Corine Ngufor
GLP and Testing Representative
CREC
Assistant Professor, Medical Entomology
Dr Corine Ngufor is Assistant Professor of medical entomology at the London School of Hygiene & Tropical Medicine and lead scientist at the CREC/PAMVERC Research unit in Benin. Her research focuses on the identification of new vector control tools for improved control of pyrethroid-resistant malaria vectors. Corine has several years of experience in the evaluation of vector control products. She has led several IVCC, Industry and WHO-funded research projects contributing to the development of novel LLIN and IRS products and is currently one of the lead investigators of a large-scale UNITAID/Global Fund/IVCC-funded community trial investigating the efficacy of two next-generation LLINs in Benin. As Manager of the CREC/PAMVERC unit, Corine led the Facility to Good Laboratory Practice (GLP) certification becoming the first in West Africa to achieve this status for vector control product evaluation. She has also contributed to the development of high level standard operating procedures and WHO guidelines for evaluating new vector control tools.Hilary Ranson
Methods Representative
Liverpool School of Tropical Medicine
Professor, Medical Entomology
Professor Hilary Ranson is a vector biologist whose research focuses on the control of mosquito borne disease, particularly on the use of insecticides in public health. She has led several international consortia to develop and evaluate new approaches for malaria control and currently leads a major interdisciplinary programme to increase the impact of vector control in sub Saharan Africa by filling capacity gaps, strengthening linkages between research and policy, and integrating approaches to target multiple vector borne diseases. Professor Ranson is a member of the Vector Control Advisory Group and provides additional ad hoc technical support to WHO. She works closely with industry partners and has established a testing service at LSTM to evaluate potential new vector control tools against a range of characterized mosquito populations from the field.Graham Small
Product Development, GLP and Methods Representative
IVCC
Trials Quality and Project Support Manager
Graham has more than 30 years' experience in entomological research including laboratory and field studies on mosquito vectors of disease. He has expertise in pesticide resistance research, pest control product efficacy testing, and the development and implementation of quality management systems compliant with the OECD principles of Good Laboratory Practice. Following his PhD at the London School of Hygiene & Tropical Medicine (supervised by Professor Janet Hemingway) and postdoctoral research at Cardiff University, Graham took the sideways step into industry becoming Technical Director at a CRO conducting product testing for the pest control industry. He then established his own successful consultancy before joining IVCC in 2016. At IVCC, Graham is responsible for supporting the GLP certification of collaborating African trials facilities, trials capacity resource planning, quality management and facility relationship management. He is also technical lead and support on new and repurposed active ingredient projects, insecticide analysis, formulation and biochemistry projects. Graham is a Member of the UK Research Quality Association and Fellow of the Royal Entomological Society. He was previously a consultant to WHO on GLP certification and was for 10 years a member of IVCC’s External Scientific Advisory Committee (ESAC).Sheila Tamara Shawa-Musonda
Africa Policy Representative
