Ifakara Health Institute (Ifakara & Bagamoyo)

Facility Details

Region East Africa

GLP Lead IVCC

GLP Compliance Progress

Status 1. Site Development

GLP Compliance Target 2019 Q2

Product Testing

IRS

Lab Trials (Phase I)
Small Scale Trials (Phase II)
Small Scale Trials (Phase III)

LLINS

Lab Trials (Phase I)
Small Scale Trials (Phase II)
Small Scale Trials (Phase III)

SPACE SPRAYS

Lab Trials (Phase I)
Lab Trials (Phase II)
Lab Trials (Phase III)

LARVICIDES

Lab Trials (Phase I)
Small Scale Trials (Phase II)
Lab Trials (Phase I)

TOPICAL REPELLENTS

Lab Trials (Phase I)
Small Scale Trials (Phase II)
Small Scale Trials (Phase III)

GENETICALLY MODIFIED MOSQUITOES

Lab Trials (Phase I)
Lab Trials (Phase II)
Lab Trials (Phase III)

Capacity and Features

Number of huts 28

Style of Huts Ifakara

Any Other Facilities 8 Semi-field Systems; 20 ambient chamber tests, molecular laboratory

Laboratory Strains
- Strain Names & Species

Anopheles gambiae s.s. (Ifakara susceptible);
Anopheles gambiae s.s. (Kisumu susceptible);
Anopheles gambiae s.s. (Kisumu KDR);
Anopheles arabiensis (Kingani, P450);
Anopheles funestus (Ifakara, P450);
Aedes aegypti (Bagamoyo, susceptible);
Culex quinquefasciatus (Bagamoyo).

Anopheles gambiae s.s. (Ifakara);
Anopheles gambiae s.s. (Kisumu) fully susceptible to all classes of insecticides;
Anopheles gambiae (Kisumu KDR) 80% survival of pyrethroid exposure, KDR East.

Anopheles arabiensis Kingani is resistant to all classes of pyrethroids, susceptible to all other classes  >80% survival of pyrethroids but 100% susceptible to organophosphates, DDT and carbamates.

Aedes aegypti Bagamoyo is fully susceptible to all classes of insecticides.

Wild Populations (and Resistance Profiles) - Species

Anopheles arabiensis (CyP450, 50% survival of pyrethroid exposure).
Anopheles funestus (CyP6a9b, A2965 RDL, L119-GSTe2 N485l-Ace-1).
Aedes aegypti Bagamoyo is fully susceptible to all classes of insecticides.

Resistant to all classes of pyrethroids, susceptible to all other classes.0.05% lambda cyhalothrin (22% mortality) 0.75% permethrin (38% mortality) and resistance to 0.05% deltamethrin (90% mortality).

Mosquitoes were 100% susceptible to 4% DDT, 4% dieldrin, 0.1% bendiocarb 0.025% pyrimiphos methyl, 1% fenitrothion and 5% malathion.

Hut testing possible in the following months of the year

  • january
  • february
  • march
  • april
  • may
  • june
  • november
  • december
  • Village Scale Trials possible in the following months of the year

    • ht-january
    • ht-february
    • ht-march
    • ht-april
    • ht-may
    • ht-june
    • ht-november
    • ht-december

    Contact Details

    Contact Sarah Moore / Emmanuel Mbuba

    Phone Number  +255 766468565

    Email Address smoore@ihi.or.tz / embuba@ihi.or.tz

    Website http://www.ihi.or.tz/vector-control-product-testing