Ifakara Health Institute (Ifakara & Bagamoyo)

Facility Details

Region
East Africa

GLP Lead
IVCC

GLP Compliance Progress

Status 1. Site Development

GLP Compliance Target 2019 Q4

Product Testing

IRS

  • Lab Trials (Phase I)
  • Small Scale Trials (Phase II)
  • Large Scale Trials (Phase III)

LLINS

  • Lab Trials (Phase I)
  • Small Scale Trials (Phase II)
  • Large Scale Trials (Phase III)

SPACE SPRAYS

  • Lab Trials (Phase I)
  • Small Scale Trials (Phase II)
  • Large Scale Trials (Phase III)

LARVICIDES

  • Lab Trials (Phase I)
  • Small Scale Trials (Phase II)
  • Large Scale Trials (Phase III)

TOPICAL REPELLENTS

  • Lab Trials (Phase I)
  • Small Scale Trials (Phase II)
  • Large Scale Trials (Phase III)

GENETICALLY MODIFIED MOSQUITOES

  • Lab Trials (Phase I)
  • Small Scale Trials (Phase II)
  • Large Scale Trials (Phase III)

Laboratory Strains
- Strain Names & Species

Anopheles gambiae s.s. (Ifakara susceptible);
Anopheles gambiae s.s. (Kisumu susceptible);
Anopheles gambiae s.s. (Kisumu KDR);
Anopheles arabiensis (Kingani, P450);
Anopheles funestus (Ifakara, P450);
Aedes aegypti (Bagamoyo, susceptible);
Culex quinquefasciatus (Bagamoyo).

Anopheles gambiae s.s. (Ifakara);
Anopheles gambiae s.s. (Kisumu) fully susceptible to all classes of insecticides;
Anopheles gambiae (Kisumu KDR) 80% survival of pyrethroid exposure, KDR East.

Anopheles arabiensis Kingani is resistant to all classes of pyrethroids, susceptible to all other classes  >80% survival of pyrethroids but 100% susceptible to organophosphates, DDT and carbamates.

Aedes aegypti Bagamoyo is fully susceptible to all classes of insecticides.

Wild Populations (and Resistance Profiles) - Species

Anopheles arabiensis (CyP450, 50% survival of pyrethroid exposure).
Anopheles funestus (CyP6a9b, A2965 RDL, L119-GSTe2 N485l-Ace-1).
Aedes aegypti Bagamoyo is fully susceptible to all classes of insecticides.

Resistant to all classes of pyrethroids, susceptible to all other classes.0.05% lambda cyhalothrin (22% mortality) 0.75% permethrin (38% mortality) and resistance to 0.05% deltamethrin (90% mortality).

Mosquitoes were 100% susceptible to 4% DDT, 4% dieldrin, 0.1% bendiocarb 0.025% pyrimiphos methyl, 1% fenitrothion and 5% malathion.


Hut testing possible in the following months of the year

  • january
  • february
  • march
  • april
  • may
  • june
  • november
  • december

Village Scale Trials possible in the following months of the year

  • ht-january
  • ht-february
  • ht-march
  • ht-april
  • ht-may
  • ht-june
  • ht-november
  • ht-december

Contact Details

Contact
Sarah Moore / Emmanuel Mbuba

Phone Number
 +255 766468565

Email Address
smoore@ihi.or.tz
embuba@ihi.or.tz

Website
http://www.ihi.or.tz/vector-control-product-testing